of the whole article in a thesis or dissertation. Bioinorganic chemistry is a field that examines the role of metals in biology. with the reproduced material. it in a third party non-RSC publication you must Bioorganic Chemistry publishes research that addresses biological questions at the molecular level, using organic chemistry and principles of physical organic chemistry. Find another journal best suited to publish your research. Many biological processes such as respiration depend upon molecules that fall within the realm of inorganic chemistry. L. G. F. Lopes, E. M. Carvalho and E. H. S. Sousa, Group of Bioinorganic, Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Brazil, Instituto Nacional de Ciência e Tecnologia em Tuberculose, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil, Université de Toulouse, Université Paul Sabatier, UPS, 118 Route de Narbonne, F-31062, Toulouse, Cedex 9, France, Instructions for using Copyright Clearance Center page. Latest issues. Fetching data from CrossRef. Bioinorganic Chemistry of Alzheimer’s Disease. Isoniazid is a front-line prodrug used against TB with appealing features for coordination chemists, which have been explored in a series of cases reported here. If you are the author of this article you do not need to formally request permission Bioinorganic Chemistry and Applications publishes research in all aspects of bioinorganic chemistry, including bioorganometallic chemistry and applied bioinorganic chemistry, and applications in fields such as medicine and immunology. Information about reproducing material from RSC articles with different licences Along these lines, we describe how metals as targets can cross paths with metals used as selective therapeutics, where we mainly review heme-based sensors, DevS and DosT, as a key system in the Mtb dormancy process and a current drug target. to access the full features of the site or access our. For more information contact us at info@libretexts.org or check out our status page at https://status.libretexts.org. Reproduced material should be attributed as follows: If the material has been adapted instead of reproduced from the original RSC publication This page was auto-generated because a user created a sub-page to this page. or in a thesis or dissertation provided that the correct acknowledgement is given In all cases the Ref. 375–467 (1978) Volume 9, Issue 4. pp. 469–549 (1978) Volume 9, Issue 5. pp. Kasper P. Kepp * View Author Information. We use cookies to help provide and enhance our service and tailor content and ads. Go to our eduardohss@dqoi.ufc.br, b https://doi.org/10.1016/S0006-3061(00)80131-3, https://doi.org/10.1016/S0006-3061(00)80132-5, https://doi.org/10.1016/S0006-3061(00)80133-7, https://doi.org/10.1016/S0006-3061(00)80134-9, https://doi.org/10.1016/S0006-3061(00)80135-0, https://doi.org/10.1016/S0006-3061(00)80136-2, https://doi.org/10.1016/S0006-3061(00)80137-4, https://doi.org/10.1016/S0006-3061(00)80147-7, Coordination of imidazole by hemin in organic and aqueous organic solvents, Characterization of nickel(II) bovine carbonic anhydrase and its inhibitor derivatives, Conformational aspects of superoxide-dismutase-active copper chelates and catechols, Effect of tyrosine residues on complexing of copper(II) by sulfhydryl-containing tripeptides: Its implication for tyrosine residues in blue copper proteins, Oscillation reactions in the system: Metabolites of krebs cycle-Mn, Free base porphyrin reduction potentials: A useful structure-reactivity parameter, Characterization of gold in the cytosol of rat-kidney cortex cells. Instituto Nacional de Ciência e Tecnologia em Tuberculose, Pontifícia Universidade Católica do Rio Grande do Sul, Porto Alegre, Brazil, c Bioinorganic Chemistry deals with the study of metals, inorganic elements in biological systems. DTU Chemistry, Technical University of Denmark, DK 2800 Kongens Lyngby, Denmark *E-mail: [email protected] Cite this: Chem. * 6 months). It is correlated with inorganic chemistry and biochemistry. XX is the XXth reference in the list of references. This may take some time to load. Watch the recordings here on Youtube! This disease remains a current health issue causing over 1.4 million of deaths per year. If you are the author of this article you still need to obtain permission to reproduce the whole article in a third party publication with the exception of reproduction We also acknowledge previous National Science Foundation support under grant numbers 1246120, 1525057, … Rev. Bioinorganic Chemistry. Thus, our understanding of this phenomenon may lead to a rational design of new drugs. If you are not the author of this article and you wish to reproduce material from The Journal of Inorganic Biochemistry is an established international forum for research in all aspects of Biological Inorganic Chemistry. Copyright © 2020 Elsevier B.V. All rights reserved. "Reproduced from" can be substituted with "Adapted from". The emergence of multi- (MDR) and extensively-drug resistant (XDR) Mycobacterium tuberculosis (Mtb) strains along with a long dormancy process, place major challenges in developing new therapeutic compounds. Publication Date (Web): July 13, 2012. The LibreTexts libraries are Powered by MindTouch® and are supported by the Department of Education Open Textbook Pilot Project, the UC Davis Office of the Provost, the UC Davis Library, the California State University Affordable Learning Solutions Program, and Merlot. ). This journal is no longer active on ScienceDirect. E-mail: The scope of the journal covers a range of topics at the organic chemistry-biology interface, including: enzyme catalysis, biotransformation and enzyme inhibition; nucleic acids chemistry; medicinal chemistry; natural product chemistry, natural … do not need to formally request permission to reproduce material contained in this article provided that the correct acknowledgement is given with the reproduced material. You do not have JavaScript enabled. Instructions for using Copyright Clearance Center page for details. Isoniazid is inactive against dormant Mtb, a hard to eliminate state of this bacillus, found in one-fourth of the world's population and directly implicated in the lengthy treatment of TB (ca. 2012, 112, 10, 5193–5239. Université de Toulouse, Université Paul Sabatier, UPS, 118 Route de Narbonne, F-31062, Toulouse, Cedex 9, France. Original papers of a high scientific level are published in the form of Articles (full length papers), Short Communications, Focused Reviews and Bioinorganic Methods. Volume 9, Issue 6. pp. A bioinorganic chemistry perspective on the roles of metals as drugs and targets against Mycobacterium tuberculosis – a journey of opportunities Luiz G. F. Lopes, ab Edinilton Muniz Carvalho ac … Bioinorganic Chemistry also refers to study of structure, function, mechanism, dynamics, synthesis, biotransformations of inorganic elements. We also acknowledge previous National Science Foundation support under grant numbers 1246120, 1525057, and 1413739. Corresponding authors, a Looking for an author or a specific volume/issue? is available on our Permission Requests page. The LibreTexts libraries are Powered by MindTouch ® and are supported by the Department of Education Open Textbook Pilot Project, the UC Davis Office of the Provost, the UC Davis Library, the California State University Affordable Learning Solutions Program, and Merlot. Missed the LibreFest? Have questions or comments? Group of Bioinorganic, Department of Organic and Inorganic Chemistry, Federal University of Ceará, Fortaleza, Brazil Legal. 281–371 (October 1978) Volume 9, Issue 3. An isoniazid iron-based compound, called IQG-607, has caught our attention, whose in vitro and in vivo studies are advanced and thoroughly discussed, along with other metal complexes. Overall, we report new opportunities for bioinorganic chemists to tackle this longstanding and current threat. to reproduce figures, diagrams etc. Medicinal inorganic chemists have provided many strategies to tackle a myriad of diseases, pushing forward the frontiers of pharmacology. contained in this article in third party publications Book: Bioinorganic Chemistry (Bertini et al. formally request permission using Copyright Clearance Center.

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